Covid-19: Are cloth masks still effective? And other questions answered
نویسندگان
چکیده
Aim: The aim of this study was to investigate heat shock protein 90 (HSP90) and topoisomerase I (Topo I) expression the association between both proteins clinicopathological parameters colorectal cancer (CRC), in order describe their role tumor biology regarding Kirsten Ras (KRAS) – positive/negative cases. Materials Methods: Expression HSP90 Topo I, KRAS gene mutations were estimated primary CRCs. Results: HSP90/Topo immunophenotype correlated with gender, Duke staging, grade lymph node metastasis (p<0.01). Positive correlation found mutation (p=0.02). HSP90, expression, co-expression unfavorable CRCs respect status (p<0.001). Conclusion: Our results revealed that cooperation exists CRCs, independently status, suggesting might be considered as a double target on individual cells.
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ژورنال
عنوان ژورنال: BMJ
سال: 2021
ISSN: ['0959-8138']
DOI: https://doi.org/10.1136/bmj.n432